Rulers over randomness: stroma cells guide lymphocyte migration in lymph nodes

Publication information:

Mempel T, Junt T, Andrian U. Rulers over randomness: stroma cells guide lymphocyte migration in lymph nodes. Immunity. 2006;25(6):867–9. doi:10.1016/j.immuni.2006.11.002

Abstract

How is the amoeboid movement of lymphocytes in secondary lymphoid organs orchestrated? In this issue of Immunity, Bajénoff et al. (2006) demonstrate that stromal cell networks serve as guidance structures that direct and limit the migration of B and T cells in lymph nodes.