von Andrian Lab Videos
 

 

THE CC CHEMOKINE THYMUS-DERIVED CHEMOTACTIC AGENT 4 (TCA-4, SECONDAY LYMPHOID TISSUE CHEMOKINE, 6CKINE, EXODUS-2) TRIGGERS LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN 1-MEDIATED ARRESTED OF ROLLING T LYMPHOCYTES IN PERIPHERAL LYMPH NODE HIGH ENDOTHELIAL VENULES

Video One

Localization of CCL21 in Wildtype PLN-HEV.


T-GFP Cells in PLN-HEV of a Wildtype Mouse


Video Three

Localization of CCL21 in PLT/PLT PLN HEV


Video Four

T-GFP Cells in PLN-HEV of a PLT/PLT Mouse


Localization of IC Injection of CCL21 in HEV PLT/PLT PLN


 

Video Six

1 Hour After Intracutaneous Injection of CCL21

 


For details on experimental methods & techniques see:
Stein, J.V., Rot, A., Luo, Y., Narasimhaswamy, M., Nakano, H., Gunn, M.D., Matsuzawa, A., Quackenbush, E.J. Dorf, M.E., and von Andrian, U.H. The CC Chemokine Thymus-derived Chemotactic Agent 4 (TCA-4, Secondary Lymphoid Tissue Chemokine, 6Ckine, Exodus-2) Triggers Lymphocyte Function-associated Antigen 1-mediated Arrest of Rolling T Lymphocytes in Peripheral Lymph Node High Endothelial Venules. J. Exp. Med. 191: 61-75, 2000. [Full Text PDF]